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116076 trials found · Page 2955 of 5804
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Brain stimulation shows promise for easing OCD symptoms
Symptom relief CompletedThe purpose of this study is to test the efficacy of 1-Hz repetitive transcranial magnetic stimulation (TMS) over the pre-supplementary motor area as a treatment for obsessive compulsive disorder. Additionally, this study aims to identify the mechanisms of action of TMS and poten…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Dialysis patients try exercise to ease symptoms
Symptom relief CompletedThe purpose of this study is to determine whether participation in a 26-week exercise rehabilitation program is effective at reducing symptom burden and improving quality of life in individuals receiving chronic hemodialysis.
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Can a light bulb heal the brain? VA tests LED therapy for vets
Symptom relief CompletedThis study investigates the efficacy of a novel neuromodulation treatment, light emitting diodes (LED), on cognition, neuropsychiatric status and quality of life in individuals with traumatic brain injury (TBI).
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Hat-Trick for baby brains: new monitor could spot injury sooner
Knowledge-focused Recruiting nowThe purpose of this study is to improve the ability of the investigators to monitor brain health in newborn babies at risk of brain injuries. The researchers will be using an investigational system of devices to non-invasively (that, is, without penetrating the skin), measure the…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can a cholesterol drug help stop vitiligo?
Disease control CompletedCondition: Non segmental and active vitiligo of adulthood. Main objective: To evaluate the efficacy of a daily treatment with atorvastatin 80mg/d combined to UVB compared to UVB alone in active vitiligo after 6 months of treatment. Methods: Prospective interventional bicentr…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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4,000 healthy adults scanned to stop heart disease before it starts
Knowledge-focused OngoingThe Miami Heart Study at Baptist Health will be an observational, longitudinal and prospective cohort study in a target population of 4000 healthy subjects (40-65 years old) consisting of members from the Greater Miami Area (including eligible BHSF(Baptist Health South Florida) e…
Sponsor: Baptist Health South Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Blood test may unlock hidden cause of heart failure
Diagnosis OngoingThe purpose of this study is to evaluate existing biomarkers and see if they can be used to accurately diagnose the etiology of heart failure.
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Could a simple bandage help sepsis patients? new study explores
Symptom relief CompletedEarly and adequate fluid resuscitation (\< 6 hours) in patients with circulatory failure is essential but may exacerbate oedema, which may itself: 1) aggravate pulmonary lesions and prolong mechanical ventilation, 2) aggravate organ failure and 3) increase mortality notably in pa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Can a common painkiller stop brain tumors? new study hopes to find out
Disease control OngoingCancer that has spread to the brain, or brain metastasis, is difficult to treat. Meclofenamate is a drug which has been shown to reduce brain metastasis growth in the laboratory. This medicine has been used in the past to treat pain. But, in this study, it will be used to prevent…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New drug combo shows promise in Hard-to-Treat breast cancer
Disease control CompletedThis research study is a way of gaining new knowledge about the combination of Taselisib with other drugs in the treatment of metastatic breast cancer. Taselisib is an investigational drug which works by blocking a protein called PI3K (phosphoinositide 3-kinase) that helps cancer…
Phase: PHASE1 • Sponsor: Otto Metzger, MD • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New therapy aims to ease spiritual distress in latino cancer patients
Symptom relief Recruiting nowThe purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones. Latinos often experience greater challenges due to the cancer. However, few studies and …
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New drug shows promise in early trial for advanced cancers
Disease control CompletedThe study is a first in man, dose escalation study to evaluate the safety, tolerability and how the drug works in the body in patients with all solid tumours. The aim of this study is to determine the most effective dose of the study drug that can then be further investigated in …
Phase: PHASE1 • Sponsor: Royal Marsden NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Can taking drug holidays make prostate cancer treatment last longer?
Disease control OngoingAbiraterone is approved in the United States by the U.S. Food and Drug Administration (FDA) to treat metastatic prostate cancer at 1000 mg daily. The purpose of this study is to find out if an on and off schedule of taking abiraterone would prolong the participant's cancer's res…
Phase: EARLY_PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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AI outperforms traditional methods in predicting Post-Surgery bowel issues
Knowledge-focused CompletedFollowing thorough screening based on inclusion and exclusion criteria, patients from the two sizable medical centers were split up into two cohorts for this study. Cohort 1 served primarily as the training and internal validation set, while Cohort 2 was used for external validat…
Sponsor: Northern Jiangsu People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Massage may ease chemo nerve damage
Symptom relief OngoingThis clinical trial studies massage therapy in reducing chemotherapy-induced nerve problems (peripheral neuropathy) that may cause pain, numbness, tingling, swelling, or muscle weakness in different parts of the body in patients with gastrointestinal or breast malignancies. Massa…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Less invasive surgery shows promise for anal cancer in HIV patients
Disease control CompletedThis phase II trial studies surgery in treating patients with anal canal or perianal cancer that is small and has not spread deeply into the tissues and human immunodeficiency virus (HIV) infection. Local surgery may be a safer treatment with fewer side effects than bigger surger…
Phase: PHASE2 • Sponsor: AIDS Malignancy Consortium • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Farm fresh foods for healthy kids: a recipe for preventing obesity?
Prevention CompletedThe purpose of this study is to better understand how participation in cost-subsidized community supported agriculture programs paired with tailored education can affect diet quality and energy balance among children in low-income households.
Phase: NA • Sponsor: Cornell University • Aim: Prevention
Last updated Jun 27, 2026 09:03 UTC
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Could a simple nerve stimulator ease bladder troubles in Parkinson's?
Symptom relief CompletedOnly one study has evaluated the effect of TENS in LUTD in Parkinson's syndromes. It was reported at the congress of the "Société Interdisciplinaire Francophone d'UroDynamique et de Pelvi-Perinéologie" (SIFUD-PP) in 2011 by Ohanessian et al., and comprised 6 female patients with …
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Nose injection may ease pain after sinus surgery
Symptom relief CompletedEndoscopic sinus surgery (ESS) is a prevalent surgical procedure. It is required in many chronic rhinosinusitis for whom the medical treatment failed. In order to improve the postoperative management of patients treated with ESS, we aim to assess the analgesic action of local inj…
Phase: PHASE3 • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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DASH diet and lifestyle advice tested as Drug-Free blood pressure strategy
Disease control CompletedThis pilot randomized controlled trial evaluated the effects of the Dietary Approaches to Stop Hypertension (DASH) diet and lifestyle modification on blood pressure in adults with prehypertension. The study was conducted among adults aged 20-64 years who were diagnosed with prehy…
Phase: NA • Sponsor: Antalya Bilim University • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC