Ancient pills take on thyroid nodules: new trial tests xiaojin and neixiao luoli
NCT ID NCT07340177
First seen Jan 17, 2026 · Last updated Jun 19, 2026 · Updated 27 times
Summary
This phase 4 trial tests whether two traditional Chinese patent medicines, Xiaojin Pill and Neixiao Luoli Pill, can safely reduce the size of benign or low-risk thyroid nodules. 108 adults aged 18-65 will be randomly assigned to take one of the pills or receive only lifestyle advice for 12 weeks. The study will measure changes in nodule volume and symptom scores using ultrasound and blood tests.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, 310014, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Xiaojin Pill and Neixiao Luoli Pill (traditional Chinese patent medicines)
What this could lead to
If successful, this could offer a non-surgical option to shrink benign thyroid nodules and ease related symptoms.
What could go wrong
This is a small, early-phase trial with only 108 participants. The medicines are traditional Chinese remedies with limited evidence, and results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.