Thyroid nodule study seeks best treatment for patients
NCT ID NCT05189314
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two treatments for non-cancerous thyroid nodules: surgery and radiofrequency ablation. Researchers will track how much the nodules shrink, changes in thyroid hormone levels, and quality of life. About 100 adults with benign nodules will participate, and the goal is to learn which treatment works better.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2019
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (\>/=18 years) with benign, non-functional benign thyroid nodules
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients \>/=18 years old with benign thyroid nodules Exclusion Criteria: * cardiac arrhythmia * pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Columbia University
RECRUITINGNew York, New York, 10032, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- AI predicts success of heat treatment for thyroid lumps
- New ultrasound probe and AI aim to sharpen thyroid nodule detection
- Blue spray may shield nerves during thyroid surgery
- New hope for goiter sufferers: blocking blood flow to nodules may ease breathing trouble
- Herbal pills tested as possible treatment for thyroid nodules