Herbal pills tested as possible treatment for thyroid nodules

NCT ID NCT07340177

Not yet recruiting Disease control Sponsor: Zhejiang Provincial People's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 4 trial tests whether two traditional Chinese medicines, Xiaojin Pill and Neixiao Luoli Pill, can safely reduce the size of benign or low-risk thyroid nodules. About 108 adults aged 18 to 65 will be randomly assigned to take one of the pills or receive only lifestyle advice for 12 weeks. The study will compare changes in nodule volume and symptoms using ultrasound and questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Xiaojin Pill and Neixiao Luoli Pill (traditional Chinese patent medicines)
What this could lead to: If effective, these pills could offer a non-surgical option to shrink benign thyroid nodules and ease related symptoms.
What could go wrong: This is a small, early-phase trial with only 108 people. The pills may not work better than lifestyle changes alone, and long-term safety is unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nodular goiter Thyroid Nodule

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

THYROID NODULES

Contacts and locations

Locations

Zhejiang Provincial People's Hospital

Hangzhou, Zhejiang, 310014, China

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