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850 volunteers join hunt for earliest Alzheimer's clues

NCT ID NCT03140865

First seen Apr 02, 2026 · Last updated Jun 19, 2026 · Updated 11 times

Summary

This study follows 850 adults with normal cognition or mild memory issues to identify early risk factors for Alzheimer's disease. Researchers will track changes in memory, brain scans, and spinal fluid markers over time, with a special focus on how blood sugar and insulin problems may contribute. The goal is to better understand the disease's earliest stages to improve future prevention and treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wake Forest Baptist Health

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify early warning signs and risk factors for Alzheimer's, guiding future prevention or treatment strategies.

What could go wrong

This is an observational study, not testing a treatment. It may not directly lead to new therapies, and results may take years to impact patient care.

Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.