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Hands-on therapies put to the test for period pain relief

NCT ID NCT07731243

Symptom relief Sponsor: Istanbul Medipol University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial compares three drug-free therapies—vibration therapy, classical abdominal massage, and myofascial release—against standard education alone for women aged 18 to 30 with primary dysmenorrhea (painful periods). Participants will receive their assigned treatment twice a week for 12 weeks. The study measures changes in pain severity, pressure pain threshold, and menstrual symptoms to see which approach offers the most relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
vibration therapy, classical abdominal massage, and myofascial release
What this could lead to
If one of these hands-on therapies proves effective, it could offer women a drug-free option for managing painful periods.
What could go wrong
This is a small, early-stage trial with no blinding for participants, so results may be influenced by placebo effects. The therapies require multiple clinic visits, which may limit real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 96 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* Inclusion Criteria: * Female participants aged 18 to 30 years. * Having regular menstrual cycles during the previous 6 months. * Having a diagnosis consistent with primary dysmenorrhea following evaluation by an obstetrician and gynecologist. * Experiencing menstrual pain in at least 2 of the previous 3 menstrual cycles. * Having menstrual pain intensity of 4 or higher on a 0-10 Visual Analog Scale. * Voluntarily agreeing to participate in the study and providing written informed consent. Exclusion Criteria: * Secondary dysmenorrhea. * Diagnosis of endometriosis, uterine fibroids, ovarian cysts, or pelvic inflammatory disease. * History of gynecological surgery. * Pregnancy or suspected pregnancy. * Having given birth within the previous 6 months. * Recent initiation of hormonal treatment. * Chronic pelvic pain or a neurological, rheumatological, or systemic inflammatory disease. * Having received manual therapy or physiotherapy targeting the abdominal or lumbopelvic region within the previous 3 months. * Skin lesions, infection, open wounds, or other dermatological conditions in the treatment regions. * Any clinical condition considered a contraindication to vibration therapy. * Inability to comply with the study protocol -

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Conditions

The condition(s) this trial relates to.

Dysmenorrhea primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dysmenorrhea primary

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istanbul Medipol University

    RECRUITING

    Istanbul, Istanbul, 34815, Turkey (Türkiye)

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