Ultrasound may replace X-Ray for back pain injections, new trial hopes
NCT ID NCT07627308
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests if using ultrasound to guide a nerve root injection works as well as the standard X-ray method for treating lower back and leg pain from irritated nerves. Sixty-four adults aged 18 to 75 will receive one injection of steroid and numbing medicine, then be followed for 3 months. The goal is to see if ultrasound can provide similar pain relief without exposing patients to radiation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- steroid and numbing medicine injection
- What this could lead to
- If successful, this could show that ultrasound guidance is a safe and effective alternative to X-ray for these injections, avoiding radiation exposure for patients.
- What could go wrong
- This is a small, early-stage trial with only 64 participants, so results may not apply to everyone. The study compares two procedures, not a new treatment, so it won't lead to a cure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 64 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 75 years. * Clinical diagnosis of lumbar radiculopathy characterized by radicular pain, paresthesia, or weakness in a dermatomal distribution. * Magnetic Resonance Imaging (MRI)-confirmed nerve root compression due to disc herniation or foraminal stenosis. * Failure to respond to at least 3 months of conservative medical treatment. * Radiculopathy affecting the L4, L5, or combined L5-S1 levels (where the primary symptomatic level can be reliably targeted) Exclusion Criteria: * Isolated S1 radiculopathy. * Significant spinal deformities, including scoliosis \>20° or spondylolisthesis \>Grade II. * History of prior lumbar spine surgery. * Bleeding disorders (International Normalized Ratio \[INR\] \>2.5). * Severe uncontrolled diabetes mellitus (HbA1c \>8%). * Advanced cardiac, renal, or hepatic disease. * Active systemic infection or localized infection at the injection site. * Known allergies to corticosteroids or local anesthetics. * Presence of progressive neurological deficits or cauda equina syndrome. * Peripheral neuropathies mimicking radiculopathy. * Pregnancy or breastfeeding. * Severe psychiatric illness or cognitive impairment affecting study compliance.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Medicine, Tanta University.
RECRUITINGTanta, Gharbia Governorate, 31527, Egypt
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