New nerve block could improve recovery after mastectomy
NCT ID NCT07647367
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times
Summary
This study compares two types of nerve blocks given before breast cancer surgery (modified radical mastectomy) to see which one helps patients recover better. Sixty women will receive either a newer block called subtransverse interligamentary plane block or the standard thoracic paravertebral block. The main goal is to measure recovery quality using a questionnaire that covers pain, comfort, emotions, and independence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (local anesthetic injection)
- What this could lead to
- If successful, this could show that a newer, potentially safer nerve block provides recovery quality as good as the standard block after mastectomy.
- What could go wrong
- This is a small, early-stage trial with only 60 participants. It may not prove the new block is better, and results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult female patients aged 18 to 65 years with American Society of Anesthesiologists (ASA) Physical Status I - III, who were scheduled for unilateral MRM surgery under general anesthesia and able to understand and complete the QoR-15 questionnaire Exclusion Criteria: * • Patients declined to participate in the trial. * History of allergy to the used local anesthetic (LA) drugs. * Patients with cutaneous lesions at the needle entry point. * Coagulopathy or current anticoagulant therapy contraindicating regional block. * Patients with severe hepatic, renal, cardiac, or respiratory disease. * Psychiatric or cognitive disorder interfering with QoR-15 assessment * Chronic opioid use or chronic pain syndrome. * Failed block. * Morbid obesity (body mass index \>40 kg/m2) * Intraoperative major complications requiring postoperative ICU admission. * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tanta university hospital
RECRUITINGTanta, Gharbia Governorate, 31527, Egypt
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Tanta university hospital
RECRUITINGTanta, 31527, Egypt
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