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Partial tonsil surgery may cut sick leave and opioid use

NCT ID NCT07598201

Symptom relief Sponsor: Turku University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two tonsil surgery methods in adults: full removal (extracapsular) and partial removal (intracapsular). The goal is to see if partial surgery allows a shorter sick leave and less need for opioid painkillers, while still being as effective at relieving tonsillitis symptoms after one year. Ninety adults with recurrent or chronic tonsillitis will be randomly assigned to one of the two procedures and followed for up to five years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgical procedure (extracapsular tonsillectomy vs intracapsular tonsillectomy)
What this could lead to
If it works, this could show that partial tonsil surgery allows a shorter sick leave and less need for strong painkillers, while still being as effective as full removal.
What could go wrong
This is a small, early-stage trial with only 90 adults, so results may not apply to everyone. The study is not yet recruiting, and the benefit of partial surgery may not hold up in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-65 years 2. Recurrent or chronic tonsillitis (see above) 3. Indication for surgical treatment 4. Eligible for day care surgery Exclusion Criteria: 1. Peritonsillar abscess less than month ago 2. Previous palatine tonsil surgery (excluding small incision or biopsy) 3. Current or positive history of a malignant disease 4. Anticoagulant medication 5. Contraindication to non-steroidal anti-inflammatory drugs (NSAID) or paracetamol 6. Other significant co-morbidity 7. Other contraindications determined by the investigator

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Conditions

The condition(s) this trial relates to.

tonsillitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic tonsillitis Recurrent tonsillitis

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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Other studies related to the condition(s) this trial covers.