Probiotic pill may cut Kids' sore throat episodes
NCT ID NCT07235826
First seen Nov 19, 2025 · Last updated Jun 19, 2026 · Updated 29 times
Summary
This study tests whether a probiotic called Streptococcus salivarius Evol12, taken as a daily dissolving tablet, can reduce how often children aged 3 to 11 get tonsillitis. Two hundred children with a history of frequent tonsillitis will receive either the probiotic or a placebo for three months, then switch treatments for another three months. Researchers will track episodes, antibiotic use, and school absences to see if the probiotic helps.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Università di Urbino Carlo Bo
RECRUITINGUrbino, PU (Pesaro E Urbino), 61029, Italy
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Streptococcus salivarius Evol12 probiotic tablet
What this could lead to
If it works, this could offer a simple, daily probiotic to help prevent frequent tonsillitis in children, reducing the need for antibiotics or surgery.
What could go wrong
This is an early-stage trial with only 200 children, and the effect may be small or no better than placebo. Probiotics can sometimes cause mild digestive upset.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.