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Could a common arthritis drug help fight recurrent brain cancer?

NCT ID NCT05326464

First seen Dec 18, 2025 · Last updated Jun 14, 2026 · Updated 26 times

Summary

This study tests whether Tofacitinib, a drug used for arthritis, can slow tumor growth in people with recurrent glioblastoma (a type of brain cancer). About 17 adults whose cancer returned after standard treatment will take Tofacitinib pills twice daily. The goal is to see if it extends time without tumor progression and is safe to use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.