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New hope for aggressive brain cancer: drug may stall tumor return

NCT ID NCT05326464

First seen Dec 18, 2025 · Last updated Apr 30, 2026 · Updated 19 times

Summary

This study tests whether the drug tofacitinib can slow tumor growth in people with recurrent glioblastoma, a fast-growing brain cancer. About 17 adults whose cancer has returned after standard treatment will take tofacitinib pills twice daily. The main goal is to see how long the tumor stays under control and to check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.