Could a common arthritis drug help fight recurrent brain cancer?

NCT ID NCT05326464

First seen Dec 18, 2025 · Last updated Apr 29, 2026 · Updated 18 times

Summary

This study tests whether Tofacitinib, a drug used for arthritis, can slow tumor growth in people with recurrent glioblastoma (a type of brain cancer). About 17 adults whose cancer has returned after standard treatment will take Tofacitinib pills twice daily. The main goal is to see how long the cancer stays under control and to check for side effects.

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Contacts and locations

Locations

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.