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Could an arthritis drug save lives in HIV-TB meningitis?

NCT ID NCT05590455

First seen Jan 04, 2026 · Last updated May 20, 2026 · Updated 18 times

Summary

This study tests whether adding the drug adalimumab to standard TB meningitis treatment can reduce deaths in HIV patients. About 130 adults in Brazil, Mozambique, and Zambia will take part. The goal is to see if this approach is safe and improves survival within 3 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Adult Infectious Diseases Centre, University Teaching Hospital

    NOT_YET_RECRUITING

    Lusaka, Zambia

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Instituto Nacional de Saude

    NOT_YET_RECRUITING

    Maputo, Mozambique

    Contact

    Contact Email: •••••@•••••

  • Laboratory of clinical research on STD/AIDS - IPEC/FIOCRUZ

    RECRUITING

    Rio de Janeiro, 21040-900, Brazil

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.