HIV I INFECTION

This study tests a new tuberculosis (TB) vaccine called MTBVAC in 276 adolescents and adults in South Africa, both with and without HIV. The goal is to see if the vaccine is safe and triggers a strong immune response. TB is a major threat for people with HIV, so finding a vaccine…

This study tests whether adding the drug adalimumab to standard TB meningitis treatment can reduce deaths in HIV patients. About 130 adults in Brazil, Mozambique, and Zambia will take part. The goal is to see if this approach is safe and improves survival within 3 months.

This study is testing whether a single low dose of nivolumab, a drug used in cancer treatment, can reduce the hidden HIV reservoir in people living with HIV who are on antiretroviral therapy (ART). The HIV reservoir is a group of infected cells that stay dormant and prevent a cur…

This study looks at two ways to reduce pain from HIV injections: changing the injection site (from the buttock to the hip area) and using a virtual reality headset during the shot. About 120 people with well-controlled HIV will try all four combinations of site and VR use. The go…

This study follows 250 women living with HIV in Zimbabwe who have been treated for cervical pre-cancer. Researchers want to find out how often the disease returns and which tests best predict that return. Participants will have regular check-ups and tests every six months for two…