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New Throat-Numbing technique could make awake intubation easier
NCT ID NCT07397234
First seen Jun 26, 2026 · Last updated Jul 29, 2026 · Updated 3 times
Summary
This study tests a new method for numbing the throat before inserting a breathing tube while the patient is awake. It compares two ultrasound-guided nerve block techniques in 94 adults with difficult airways. The goal is to see if the newer thyroid cartilage approach works as well as the standard method for a comfortable intubation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lidocaine
- What this could lead to
- If successful, this could offer a simpler and safer way to numb the throat for awake breathing tube insertion, reducing coughing and discomfort.
- What could go wrong
- This is a small, early-stage trial (94 participants) comparing two techniques; it may not show a clear advantage, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 94 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients scheduled for awake tracheal intubation under general anesthesia. 2. Patients with difficult airways (e.g., limited cervical spine mobility, full stomach, partial airway obstruction, craniofacial deformities or trauma, micrognathia, mouth opening \<3cm, Mallampati III or IV classification) posing challenges for mask ventilation or intubation. 3. Age between 18 and 85 years old. 4. Gender is not restricted. 5. ASA classification of I - III. Exclusion Criteria: 1. Cardiovascular dysfunction or arterial aneurysms. 2. Mental or neurological disorders or concomitant arterial aneurysms. 3. Infection at the puncture site. 4. Allergy to local anesthetics. 5. Continuous use of antiplatelet or anticoagulant medications preoperatively. 6. Hoarseness or coughing while drinking water. 7. Bronchial asthma. 8. Participation in other clinical trials within the previous 3 months before enrollment 9.r current participation in other clinical trials.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Nanjing First Hospital
COMPLETEDNanjing, Jiangsu, 210006, China
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Nanjing First Hospital
RECRUITINGNanjing, 210006, China
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