Nanjing First Hospital, Nanjing Medical University

This study tests whether adding a low dose of colchicine (a well-known anti-inflammatory drug) to standard heart treatments can lower the risk of major heart problems like heart attacks and strokes. About 3,800 adults with stable coronary artery disease and non-blocking plaque wi…

This study looks at whether improving cholesterol levels can help prevent strokes in people with moderate to severe narrowing of brain arteries. Researchers will follow 180 adults who have not had artery-opening procedures. The goal is to see if better lipid management lowers the…

This study is testing a new, less invasive heart valve implant for people with severe aortic regurgitation (a leaky heart valve). The goal is to see if this implant can reduce the risk of death, stroke, or repeat hospital visits compared to standard care. About 210 adults with se…

This study looks at whether treating Helicobacter pylori (a stomach infection) can also improve metabolic syndrome (high blood sugar, cholesterol, and weight). Researchers will give standard antibiotics to 120 adults with both conditions, and some will also get probiotics or berb…

This study compares two ways to treat heart stents that have narrowed again after drug-eluting stent placement. About 1500 adults with this condition will receive either standard angiography guidance or advanced intravascular imaging guidance during a repeat procedure. The goal i…

This study tests whether a super high-pressure balloon or a special shockwave device (intravascular lithotripsy) works better to crack open severely calcified coronary arteries before placing a stent. About 78 adults with hardened heart arteries will be randomly assigned to one o…

This study tests whether special PET scans using targeted tracers can more accurately find and stage neuroblastoma and pheochromocytoma/paraganglioma tumors than current methods. About 30 people aged 1 to 70 will receive an injection of a radioactive tracer and then have a PET sc…

This study tests different amounts of a long-lasting painkiller (liposomal bupivacaine) injected near the knee nerve to control pain after knee surgery. The goal is to find the dose that provides good pain relief without weakening the thigh muscle. About 63 adults having knee sur…

This study examines blood samples from 500 people who recently had a stroke and healthy volunteers to find RNA patterns that could help diagnose strokes and predict recovery. Researchers will use advanced genetic sequencing to identify potential biomarkers. The goal is to improve…

This study is testing whether a special CT scan can better predict who will have future heart problems after a heart attack and stent placement. Researchers will enroll 1,000 patients and follow them for up to 5 years. The goal is to create a more accurate risk score to guide per…

This study is tracking 5,000 adults hospitalized for an ischemic stroke to see how different treatment strategies affect their recovery. Researchers will collect medical records and brain scans to build models that predict outcomes. The goal is to learn which treatments work best…

This study looks at whether a laser attached to an ultrasound machine can help doctors insert a thin tube into a vein (IV) on the first try in people having heart surgery. About 100 adults aged 18 to 80 will take part. The goal is to see if the laser makes the process faster and …

This study compares two types of nerve blocks (retro-SCTLB and TPVB) to see how well they spread numbing medicine in patients having a lung nodule located with a CT scan. About 50 adults will take part. The goal is to understand which method provides better pain control during th…

This study examines tiny RNA molecules in the blood of 300 adults who had a stroke and received a procedure to remove the clot. Researchers want to see if certain RNA patterns can help predict how well patients recover. The goal is to find new markers that could guide future stro…