Ancient remedies take on early puberty: can herbs and needles slow it down?
NCT ID NCT06510764
First seen Mar 26, 2026 · Last updated Jun 24, 2026 · Updated 14 times
Summary
This study tests whether a combination of Chinese herbs (Ziyin-Xiehuo granules) and tiny acupuncture needles placed under the skin can help girls with idiopathic precocious puberty. The 170 participants will receive either the herbs plus acupuncture or a placebo. Researchers will check if breast tissue shrinks and if bone age progresses more slowly over six months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital of Fudan University
RECRUITINGShanghai, 201102, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Hospital of Fudan university
RECRUITINGShanghai, Shanghai Municipality, 201102, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ziyin-Xiehuo Chinese medicine herbs and intradermal acupuncture
What this could lead to
If it works, this could offer a natural alternative to standard hormone therapy for managing early puberty in girls.
What could go wrong
This is a Phase 3 trial, but it's relatively small (170 participants) and uses traditional medicine, which may not work for everyone. The herbs and needles could cause mild side effects like skin irritation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.