Could a simple TB test save kids with pneumonia?
NCT ID NCT03831906
First seen Dec 26, 2025 · Last updated Jun 19, 2026 · Updated 23 times
Summary
This study tested whether adding a rapid tuberculosis (TB) test to standard care for children hospitalized with severe pneumonia could reduce deaths. Over 2,500 children aged 2 to 59 months in six high-TB countries were enrolled. The test, called Xpert MTB/RIF Ultra, was done on nose and stool samples at admission to find TB early and start treatment right away.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Angré University Teaching Hospital
Abidjan, Côte d’Ivoire
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Arthur Davidson Children Hospital
Ndola, Zambia
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Biyem Assi District Hospital
Yaoundé, Cameroon
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Chantal Biya Foundation
Yaoundé, Cameroon
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Cocody University Teaching Hospital
Abidjan, Côte d’Ivoire
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Holy Innocents Children's Hospital
Mbarara, Uganda
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Jinja Regional Reference Hospital
Jinja, Uganda
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José Macamo General Hospital
Maputo, Mozambique
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Kampong Cham Provincial Referral Hospital
Kampong Cham, Cambodia
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Lusaka University Teaching Hospital
Lusaka, Zambia
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Maputo Central Hospital
Maputo, Mozambique
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Mulago National Referral Hospital
Kampala, Uganda
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National Pediatric Hospital
Phnom Penh, Cambodia
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Takeo Provincial Referral Hospital
Takeo, Cambodia
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Treichville University Teaching Hospital
Abidjan, Côte d’Ivoire
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Yopougon University Teaching Hospital
Abidjan, Côte d’Ivoire
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Xpert MTB/RIF Ultra diagnostic test
What this could lead to
If successful, this approach could help identify tuberculosis earlier in children with pneumonia, potentially reducing deaths by starting treatment sooner.
What could go wrong
This is a completed diagnostic trial, not a treatment study. The test may not significantly lower mortality, and results may vary across different settings.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.