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Could a lower tamoxifen dose prevent breast cancer in High-Risk women?

NCT ID NCT06184750

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 36 times

Summary

This study is for premenopausal women at higher-than-average risk for breast cancer. It tests whether a low dose of tamoxifen, adjusted based on each woman's response, can safely reduce breast density—a key risk factor for breast cancer. About 200 women will take part, and the goal is to find a dose that works with fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Case Western Reserve University

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Arizona Cancer Center - Prevention Research Clinic

    RECRUITING

    Tucson, Arizona, 85719, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Illinois College of Medicine - Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Kansas Cancer Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan Rogel Cancer Center

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.