Could a lower tamoxifen dose cut breast cancer risk? new trial seeks answers
NCT ID NCT06184750
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 35 times
Summary
This study tests whether a low dose of tamoxifen can safely reduce breast density—a key risk factor for breast cancer—in premenopausal women at higher-than-average risk. About 200 women will receive a response-guided dose, with adjustments based on how their breast density changes on mammograms. The goal is to find a dose that effectively lowers risk while minimizing side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Case Western Reserve University
RECRUITINGCleveland, Ohio, 44106, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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University of Arizona Cancer Center - Prevention Research Clinic
RECRUITINGTucson, Arizona, 85719, United States
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University of Illinois College of Medicine - Chicago
RECRUITINGChicago, Illinois, 60612, United States
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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