Could a lower tamoxifen dose prevent breast cancer in high-risk women?
NCT ID NCT06184750
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for premenopausal women at higher-than-average risk for breast cancer. It tests whether a low dose of tamoxifen can safely reduce breast density, which is linked to cancer risk. About 200 women will take tamoxifen, and doctors will adjust the dose if needed to get the best effect. The goal is to find a dose that works with fewer side effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Case Western Reserve University
RECRUITINGCleveland, Ohio, 44106, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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UT MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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University of Arizona Cancer Center - Prevention Research Clinic
RECRUITINGTucson, Arizona, 85719, United States
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University of Illinois College of Medicine - Chicago
RECRUITINGChicago, Illinois, 60612, United States
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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