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Broccoli extract tested as Anti-Aging skin shield

NCT ID NCT03730649

Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This early-stage study tests whether a cream made from sulforaphane, a compound found in broccoli, can improve skin aging and protect against damage from sunlight and visible light. Researchers will measure changes in skin proteins linked to aging and fragility in 12 adults. The goal is to understand if this natural compound can strengthen aging skin.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

12 people

The number who actually took part.

Started

Oct 2019

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must be over the age of 18 years old with healthy skin or moderate degree of photoaging/intrinsic aging; * Must be healthy enough to undergo skin biopsy, light irradiation, and other study procedures in the opinion of the investigator; * Must be willing to comply with the requirements of the protocol; * Must have the ability to understand and communicate with the investigator; * Participant must provide informed consent. Exclusion Criteria: * Subjects who are unable to provide informed consent; * Subject with significant medical history or current skin diseases that the investigator feels is not safe for study participation; * Subjects who have been treated with systemic retinoids or steroids within the past month prior to entry to the study; * Subjects who have been treated with topical steroids, retinoids or other topical drugs used within 2 weeks prior to entry to the study; * Recently treated or current skin diseases that would affect clinical evaluation and biopsy; * Subjects with a known allergy to broccoli. * Presence or suspicion of bleeding disorder or diathesis which would complicate biopsy. * Subjects with a history of excessive scar or keloid formation in the past 10 years. * Pregnant or nursing subjects (self-reported). * Subjects with known allergy to anesthetics used. * Patients with history of investigational drug use in the 30 days prior to entry into the study.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Skin aging

Contacts and locations

Locations

  • Cutaneous Translational Research Program, Department of Dermatology, Johns Hopkins University School of Medicine

    Baltimore, Maryland, 21287, United States

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