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Which therapy helps stroke hands most? new trial aims to find out

NCT ID NCT06750692

Symptom relief Sponsor: Afyonkarahisar Health Sciences University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study compares mirror therapy, brain stimulation (rTMS), and robotic hand training added to standard rehab for stroke patients. 120 adults who had a stroke at least 3 months ago will receive 20 sessions over 4 weeks. The goal is to see which approach best improves arm function, pain, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
mirror therapy, repetitive transcranial magnetic stimulation (rTMS), and robotic-assisted hand therapy
What this could lead to
If successful, this could show which therapy best helps stroke survivors regain arm and hand function and reduce pain.
What could go wrong
This is a small, early-phase study with no blinding, so results may not be definitive or apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Jan 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who applied to Afyonkarahisar Health Sciences University Hospital Physical Medicine and Rehabilitation Polyclinic with the diagnosis of hemiplegia after a cerebrovascular accident in the inpatient ward or as an outpatient for neurological rehabilitation after taking the anamnesis and physical examination, who met the inclusion criteria and eliminated the exclusion criteria * Female and male patients between the ages of 40-80 * stroke at least 3 months ago * voluntarily agreed to participate in the study regularly, whose health status is suitable for rehabilitation and who are medically stable * mini mental test score of 15 and above * Neurologically stable patient Exclusion Criteria: * significant comorbidities such as serious heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, arrhythmia, pacemaker) and uncontrolled hypertension * history of epilepsy, antiepileptic drug use * intracranial metal objects * intraauricular implants * cognitive dysfunction * upper extremity peripheral nerve injuries * malignancy * active infection * skin infections or open wounds in the application area * inflammatory diseases * orthopedic injuries that may limit maximum effort capacity * brain lesion or drug use history that may affect the seizure threshold * increased intracranial pressure * uncontrolled migraine * severe spasticity in the hand (MAS≥3) * contracture in the hand * have had a fracture or surgery on the hemiplegic side in the last 6 months * severe visual impairment * severe depression

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Conditions

The condition(s) this trial relates to.

nervous system disorder neuralgia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neurologic disorder Neuropathic pain Quality of life Stroke Upper extremity dysfunction

Contacts and locations

Locations

  • Afyonkarahisar Health Sciences University

    Afyonkarahisar, 0300, Turkey (Türkiye)

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