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Zapping the heart: radiation may tame stubborn arrhythmias

NCT ID NCT05439031

First seen Jan 16, 2026 · Last updated Jun 22, 2026 · Updated 30 times

Summary

This study tests a one-time, focused radiation treatment for people with ventricular tachycardia (a dangerous fast heart rhythm) that hasn't been controlled by medication or standard procedures. The treatment aims to reduce the number of episodes by at least half over a year. The trial will enroll 12 adults with an implanted defibrillator and a history of multiple episodes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam UMC location University of Amsterdam

    RECRUITING

    Amsterdam, North Holland, 1105AZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (stereotactic arrhythmia radiotherapy)

What this could lead to

If it works, this could offer a new, non-invasive treatment option for people with dangerous heart rhythm problems that haven't responded to other treatments.

What could go wrong

This is a very small, early-phase study with only 12 people, so results may not apply to everyone. The treatment involves radiation, which carries risks like damage to nearby organs.

Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac cardiac rhythm disease ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.