CT scan roadmap may improve heart ablation success
NCT ID NCT04747353
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a CT scan before a heart procedure could help doctors better target the source of a dangerous heart rhythm called ventricular tachycardia. 23 people who had a prior heart attack and needed catheter ablation took part. The approach aimed to see if using CT images to plan the procedure was feasible and safe.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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23 people
The number who actually took part.
- Started
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May 2021
- Finished
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Nov 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Indication for catheter ablation intervention with planned preoperative cardiac CT scan * Prior myocardial infarction (using the international definition of MI: Q waves or imaging evidence of regional myocardial akinesis/thinning in the absence of a non- ischemic cause with documentation of prior ischemic injury) and * One of the following monomorphic VT events within last 6 months: * A: ≥3 episodes of symptomatic VT treated with antitachycardia pacing (ATP), * B: ≥1 appropriate ICD shocks, * C: ≥3 VT episodes within 24 hr * D: sustained VT below detection rate of the ICD documented by ECG or any cardiac monitor * E: Sustained VT recorded on 12 leads ECG in the absence of ICD * Signed informed consent * Affiliated or beneficiary of health insurance Exclusion Criteria: * Unable or unwilling to provide written informed consent. * Active ischemia (acute thrombus diagnosed by coronary angiography, or dynamic ST segment changes demonstrated on ECG) or another reversible cause of VT (e.g. drug-induced arrhythmia), had recent acute coronary syndrome within 30 days thought to be due to acute coronary arterial thrombosis, or have CCS functional class IV angina. Note that biomarker level elevation alone after ventricular arrhythmias does not denote acute coronary syndrome or active ischemia. * Are known to have protruding left ventricular thrombus or mechanical aortic and mitral valves. * Have had a prior catheter ablation procedure for VT * Presenting arrhythmia: polymorphic VT or ventricular fibrillation (VF). * Are in renal failure (Creatinine clearance \<30 mL/min), have NYHA Functional class IV heart failure, or a systemic illness likely to limit survival to \<1 year. * Pregnancy, breast feeding women and women who are of childbearing age and not practicing adequate birth control. (French HAS criteria or following methods are considered adequate): * Combined hormonal contraception * Injected hormonal contraception * Implanted hormonal contraception * Progesterone-only hormonal contraception associated with inhibition of ovulation * Placement of an intrauterine device (IUD) * Placement of intrauterine hormone-realising system (IUS) * Patient under legal protection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Cardiac Pacing and Electrophysiology, CHU Bordeaux
Pessac, France
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Heart Centre, Luzerner Kantonsspital
Lucerne, Switzerland
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Other studies related to the condition(s) this trial covers.
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