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New vaccine aims to train immune system against aggressive breast cancer

NCT ID NCT05455658

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 19 times

Summary

This study tests a DNA-based vaccine called STEMVAC in 33 people with early-stage triple negative breast cancer (stages IB to III). The vaccine targets proteins found on breast cancer stem cells and aims to train the immune system to recognize and attack these cells. The main goal is to see if the vaccine triggers a strong immune response. Participants have already completed standard treatment and receive the vaccine to help prevent the cancer from coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21287, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.