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Salt vs. potassium: which wins for your arteries?

NCT ID NCT07649005

Knowledge-focused Sponsor: Florida State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether eating more potassium can protect blood vessels from the damage caused by too much salt. Thirty healthy adults aged 55-75 will follow three different diets for 10 days each, with breaks in between. Researchers will measure blood pressure, artery stiffness, and blood vessel function to see if potassium makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
controlled diets varying in sodium and potassium levels
What this could lead to
If it works, this could point toward dietary guidelines that help older adults protect their blood vessels by balancing sodium and potassium intake.
What could go wrong
This is a small, early-stage study with only 30 healthy participants, so results may not apply to everyone. It tests short-term effects, not long-term health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults ages 55-75 years * At least one-year post-menopause (females) * Willing and able to attend laboratory visits Exclusion Criteria: * BMI ≥35 kg/m2 * Seated blood pressure \>135/85 mmHg * Current diagnosis or history of cardiovascular disease, diabetes, renal disease, cancer, or major cardiovascular event (e.g. heart attack or stroke) * Taking exogenous hormones or hormone replacement therapy * Following a vegan or gluten free diet * Significant weight loss (\>10% of body weight) in the last 6 months, or actively trying to lose weight * Current or recent use of a diuretic (within the past 6 months) (e.g. spironolactone, eplerenone) * Current or recent use of a potassium binding medication (within the past 6 months) * Current use of blood pressure lowering medications (e.g. ACE inhibitors, calcium channel blockers, diuretics, vasodilators, beta blockers, AngII receptor blockers) * Current or recent use of the medication trimethoprim * Elevated blood lipids (LDL cholesterol ≥190 mg/dL) * Elevated serum potassium level (\>5.1 mmol/L) * Elevated BUN (\>22 mg/dL) * Elevated creatinine (\>1.2 mg/dL) * Low eGFR (\<90 mL/min/1.73 m²) * Current or recent use of tobacco, nicotine, or illicit drugs * Radical hysterectomy or oophorectomy (females)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy older adults

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Florida State University

    RECRUITING

    Tallahassee, Florida, 32306, United States

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