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Can a simple bleach step make tooth stains disappear?
NCT ID NCT07162077
First seen Jun 25, 2026 · Last updated Sep 11, 2026 · Updated 3 times
Summary
This study tests whether adding a sodium hypochlorite (bleach-like) solution to a standard tooth-resin treatment can better hide yellow or brown stains on front teeth caused by a condition called molar-incisor hypomineralization (MIH). Twenty-four teeth from children with MIH will be randomly assigned to get the resin treatment with or without the extra bleach step. Researchers will measure color change and ask parents how satisfied they are with the results.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sodium hypochlorite 5.25%
- What this could lead to
- If it works, this could offer a better way to lighten or mask stubborn yellow/brown stains on front teeth caused by MIH, improving smile appearance.
- What could go wrong
- This is a very small early study with only 24 teeth, so results may not apply to everyone. The treatment is cosmetic and may not fully hide the opacity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
15 people
The number who actually took part.
- Started
-
Aug 2025
- Finished
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Sep 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with MIH-related opacities on the incisal and middle thirds of the buccal surface of their permanent incisors, ac- cording to EAPD diagnostic criteria of (MIH), only isolated lesions will be selected. Exclusion Criteria: * Teeth with resin composite restorations, previously treated by exter- nal bleaching, micro-abrasion or re-mineralization(fluoride varnish or calcium-based products such asCPP-ACP) will be excluded. * Opacities present only on incisors without molar * WSLs caused by orthodomtic treatment * Teeth affected by dental fluorosis, Amelogenesis imperfecta and Tetracycline-pigmented teeth
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
TishreenU
Latakia, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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