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Dental bone graft showdown: which material keeps your jaw stronger?

NCT ID NCT07565558

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two different materials used to preserve the jawbone after a tooth is pulled. Forty adults received either a cow-derived bone graft or a human donor bone graft. Researchers measured how much the bone changed in size and density over six months using 3D scans. The goal was to see which material better maintains bone for future dental implants.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
socket preservation with xenograft (Geistlich Bio-Oss) or allograft
What this could lead to
If one material proves better, it could improve future dental implant success by preserving more bone after tooth extraction.
What could go wrong
This is a small, early-stage study with only 40 participants, so results may not apply to everyone. The materials are already used in dentistry, so no major new risks are expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Aug 2024

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Maxillary premolar or mandibular molar unsuitable for restorative treatment * Vestibular lamina width of less than 1 mm * Age between 18 and 65 years * Absence of vestibular lamina defects, such as fenestrations or dehiscences * Ability and willingness to attend scheduled follow-up visits * Provision of written informed consent Exclusion Criteria: * Alcoholism * Nicotine addiction * Immunosuppressive medications * Systemic diseases that could affect the healing of soft or hard tissues * Chemotherapy or radiation therapy to the head and neck region within the past 5 years * Poor oral hygiene * Extensive tooth loss

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • "Comfortmed" dental clinic

    Żory, Silesian Voivodeship, 44-240, Poland

  • Department of Oral Surgery of the Medical University of Silesia in Bytom

    Bytom, Silesian Voivodeship, 41-902, Poland

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