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The race to save jawbone: four socket techniques go head to head

NCT ID NCT07812883

Symptom relief Sponsor: Universidad del Desarrollo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

Researchers compare four ways to manage the tooth socket after extraction to see which best preserves jawbone and gum tissue. Adults who need a tooth removed and may later get a dental implant join the study. Participants are randomly assigned to natural healing, a d-PTFE membrane, L-PRF, or L-PRF plus a d-PTFE membrane, then have imaging and pain assessments before implant placement 12 weeks later.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Four socket management approaches: natural healing, a d-PTFE membrane, L-PRF, and L-PRF plus d-PTFE membrane
What this could lead to
If one approach preserves jawbone and gum tissue better, dentists could use it to make dental implant placement easier and more predictable after tooth extraction.
What could go wrong
This is a small, single-center study of 70 people, so the results may not apply to everyone. All four approaches are already used in dentistry, and the differences between them may turn out to be minor.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Requirement for tooth extraction with the possibility of subsequent implant-supported rehabilitation in the maxillary or mandibular premolar or molar regions. * Extraction sockets classified as Class I to Class Va according to the modified Cardaropoli classification. * American Society of Anesthesiologists (ASA) Physical Status I or II. * Ability to understand the study procedures and provide written informed consent. Exclusion Criteria: * Current treatment with bisphosphonates or systemic corticosteroids. * History of head and neck radiotherapy. * Metabolic bone disorders. * Teeth presenting with acute infectious pathology at the time of extraction. * Pregnancy or breastfeeding. * Inability or unwillingness to attend scheduled follow-up visits. * Any medical or psychological condition that, in the opinion of the investigators, could interfere with study participation or data interpretation.

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Conditions

The condition(s) this trial relates to.

Tooth Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation Alveolar ridge resorption after extraction Tooth extraction Tooth extraction site healing Tooth loss

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Universidad del Desarrollo (UDD)

    RECRUITING

    Santiago, Santiago Metropolitan, 7610315, Chile

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