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Sniff your way to quit? early trial tests scent device for cigarette cravings

NCT ID NCT07007195

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This early-phase study tests whether a device that delivers specific smells can reduce cigarette cravings and help people stop smoking. About 132 smokers will use a smartphone app with or without the scent device for a week, then report cravings and quit attempts. The goal is to see if adding scents makes quitting easier.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Inspire Device (olfactory stimulation delivery system)
What this could lead to
If it works, this could offer a new, drug-free tool to help people manage cigarette cravings and support smoking cessation.
What could go wrong
This is a very early, small pilot study (132 people) testing feasibility and initial effects. The approach may not prove effective for quitting long-term, and results may not apply to all smokers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 132 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * At least 18 years of age * Ability to read, understand and speak English * Currently smoke at least 5 cigarettes daily for one year or longer * Do not currently smoke marijuana or currently smoke marijuana but willing to not smoke during the duration of the study * Did not use electronic cigarette or vaping device in the past 90 days * Have an active smartphone that is Apple or Android based * Have phone service including a data plan * Interested in downloading the study app onto their personal phone * Motivated to quit smoking * English literacy of 7th grade or higher, as indicated by a score of ≥ 4 on the Rapid Estimate of Adult Literacy in Medicine-Short Form (REALM-SF) * Biochemical verification of smoking status * Proof of smoking status at enrollment via photo of cigarettes * Presents a photo ID that matches the information on screener survey * Willing and able to complete study procedures * Willing to use NRT and quit smoking for 14 days (Phase I) or willing to use NRT and quit smoking for 13 weeks (Phase II) Exclusion Criteria: * Olfactory dysfunction including inability to smell, a very weak or distorted sense of smell, or sensitivity to odors * Report any allergies or negative reactions to odors/fragranced products * Being pregnant, breastfeeding, or planning to become pregnant within the next month * Report hypertension that is not under control * Have had a heart attack within the past two weeks * Those who participated in Phase I will not be eligible to participate in Phase II * Have a smartphone that is not compatible with the Insight mHealth platform * Report using electronic cigarette or vaping device in the past 90 days

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • RESTORE Laboratory: Research on Emotion, Substance Use Treatment Outcomes, Rehabilitation, and Empowerment

    RECRUITING

    Houston, Texas, 77204, United States

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