Extra Zzz's may boost metabolism in obesity
NCT ID NCT03594994
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether sleeping longer can improve how the body processes sugar in people with obesity. About 30 participants who slept less than 7 hours a night were split into two groups: one tried to sleep more, the other kept their usual habits. Researchers measured changes in insulin sensitivity to see if extra sleep made a difference.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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31 people
The number who actually took part.
- Started
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Oct 2018
- Finished
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Jul 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Sleep \<7h/night * Body mass index 25-50 kg/m2 * Altered glucose metabolism (any of the following) Fasting glucose 100-125 mg/dL or, 2-h plasma glucose 140-199 mg/dL during an oral glucose tolerance test (OGTT) or, HbA1c 5.7-6.4% or, homeostatic model assessment of insulin resistance (HOMA-IR) ≥2.0 Exclusion Criteria: * Sleep disorders 1. moderate to severe sleep apnea (apnea-hypopnea index ≥15 events/hour) 2. had ≥15 periodic limb movements per hour sleep \[PLMS\] 3. narcolepsy or insomnia * Perform shift work * Excessive caffeine or alcohol consumption * Significant organ dysfunction/disease (e.g. diabetes mellitus, kidney disease) * Liver disease other than metabolic dysfunction associated steatotic liver disease (MASLD) * Prior bariatric surgery * Pregnancy or breastfeeding * Taking medications that can affect study outcomes (alter sleep duration or glucose metabolism) * Tobacco or illicit drug use * Perform intense exercise \>70 min/wk or moderate exercise \>150 min/week * Excessive alcohol consumption (\>21 units of alcohol per week for men and \>14 units of alcohol per week for women)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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