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Gum disease and nighttime teeth grinding: is there a connection?

NCT ID NCT07053865

Knowledge-focused Sponsor: University of Siena Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at whether people with advanced gum disease (periodontitis) also grind or clench their teeth more during sleep. Researchers used a small portable device to measure muscle activity in the jaw over 24 hours in 40 adults, half with severe gum disease and half with healthy gums. The goal was to see if there is a link between gum disease and sleep bruxism, which could help guide future dental care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jun 2025

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients and healthy controls aged 28-50 years recruited at the University of Siena, Italy. The study includes both individuals with advanced periodontitis and healthy controls.

Ages

28 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 28 and 50 years * Ability to perform adequate oral hygiene * Willingness to participate and sign informed consent * For periodontitis group: Diagnosis of Stage III or IV periodontitis * For control group: Absence of periodontal disease Exclusion Criteria: * Use of removable dentures * Ongoing orthodontic treatment * Temporomandibular disorders (TMD) or orofacial pain * Use of medications affecting muscle activity * Systemic or psychiatric disorders * Diabetes

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Conditions

The condition(s) this trial relates to.

bruxism periodontitis Sleep Bruxism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bruxism Periodontitis Sleep bruxism

Contacts and locations

Locations

  • AOUS

    Siena, 53100, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.