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3-Day aligner wear may speed up teeth straightening

NCT ID NCT05905224

Symptom relief Sponsor: University of Florida Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested if wearing Invisalign aligners for 3 days instead of the usual 7 can still move teeth as planned. 40 adults with mild crowding wore aligners on either schedule. Researchers compared how well the predicted tooth movements matched the actual results and how fast teeth moved. The goal is to make orthodontic treatment faster and more predictable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Oct 2023

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Physically healthy with no relevant allergies or medical problems * Male or female between the age of 18 and 30. * Full permanent dentition except for the third molars * Class I crowded dentition primarily for the lower anterior teeth (moderate crowding - 4-6 mm - according to Little's Irregularity Index) * Good oral hygiene and absence of periodontal disease * Malocclusion to be treated with Invisalign aligners (SmartTrack) * Any ethnic group Exclusion Criteria: * Orthognathic surgical cases * An extraction treatment plan * Poor oral hygiene * Patients with syndromes or craniofacial anomalies. * The use of any other orthodontic appliance than clear aligners' (Invisalign)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic tooth movement

Contacts and locations

Locations

  • University of Florida _ Department of Orthodontics

    Gainesville, Florida, 32610-0444, United States

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