Braces breakthrough? new study tests two ways to move teeth faster

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 40 years at the time of enrollment * Systemically healthy with no chronic medical conditions affecting bone metabolism or wound healing * Requiring bilateral maxillary first premolar extraction as part of a comprehensive fixed orthodontic treatment plan * Class I or mild Class II malocclusion requiring maximum anchorage canine retraction * Fully erupted maxillary permanent dentition with no missing teeth other than planned extraction teeth * Good oral hygiene (Plaque Index ≤ 1) and healthy periodontal status (probing depth ≤ 3 mm, no bleeding on probing) * No previous orthodontic treatment * Willing to attend all scheduled appointments and comply with study protocol * Able to provide written informed consent Exclusion Criteria: * Systemic diseases affecting bone metabolism including osteoporosis, osteopenia, diabetes mellitus, thyroid disorders, or autoimmune conditions * Current use of medications affecting bone remodeling including corticosteroids, bisphosphonates, non-steroidal anti-inflammatory drugs (NSAIDs), or vitamin D supplements * Current or recent smokers (within the past 6 months) * Pregnant or breastfeeding women * History of head and neck radiation therapy * Periodontal disease or active dental infection at the time of enrollment * Skeletal Class III malocclusion or severe Class II requiring surgical intervention * Previous orthodontic treatment or orthognathic surgery * Craniofacial syndromes or cleft lip and palate * Photosensitivity disorders or use of photosensitizing medications (relevant to LLLT group) * Coagulation disorders or anticoagulant therapy (relevant to MOP group) * Uncooperative patients or those unable to maintain adequate oral hygiene throughout treatment * Parafunctional habits such as severe bruxism or tongue thrusting'