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Hair may hold clues to metabolic health after Weight-Loss surgery

NCT ID NCT07368842

Knowledge-focused Sponsor: Singapore General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how severe obesity and weight-loss surgery change natural chemicals in scalp hair. Researchers will track 60 adults—some with severe obesity scheduled for bariatric surgery and some healthy-weight controls—to see if hair chemistry can signal poor metabolic health. They will also measure how common hair thinning and muscle loss are in the first six months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple hair test to detect metabolic health problems in people with severe obesity.
What could go wrong
This is a small, early observational study (60 people) that only looks at chemical changes—it does not test any treatment. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects with severe obesity will be recruited from the Singapore General Hospital's obesity clinic, while controls will be healthy volunteers.

Ages

21 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: All subjects: 1. Age 21-70 years 2. Ability to provide informed consent Healthy weight controls: 1. BMI of 18.5-24.9 kg/m2 2. No chronic disease 3. No long-term medications Severe obesity: 1. BMI of \> 32.5 kg/m2 2. Scheduled to undergo bariatric surgery Exclusion Criteria: 1. Pregnancy 2. Any factors likely to limit adherence to study protocol 3. Any history of autoimmune or scarring alopecia (eg. alopecia areata, discoid lupus, lichen planopilaris)

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Conditions

The condition(s) this trial relates to.

alopecia metabolic disease morbid obesity Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric surgery Hair loss Metabolomics Obesity / overweight

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Singapore General Hospital

    RECRUITING

    Singapore, Singapore

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