Experimental drug combo takes on brain tumors
NCT ID NCT03514069
First seen Feb 25, 2026 · Last updated May 21, 2026 · Updated 13 times
Summary
This early-phase study tests whether adding the experimental drug ruxolitinib to standard brain cancer treatment (radiation and temozolomide) is safe and tolerable for people with newly diagnosed high-grade gliomas or glioblastoma. About 60 participants will receive the combination to find the best dose and monitor side effects. The goal is to see if this approach can help control these aggressive brain tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center
Cleveland, Ohio, 44195, United States
Conditions
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