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One shot to stop pain: nerve block may prevent chronic pain after breast surgery

NCT ID NCT06019325

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times

Summary

This study tested whether a single injection of numbing medicine between the ribs can reduce chronic pain after mastectomy. 254 women having breast cancer surgery received either the nerve block or no block. Researchers checked for pain at 3 and 6 months after surgery. The goal was to see if the block lowers the chance of long-term pain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Muğla Training and Research Hospital

    Muğla, MENTEŞE, 48000, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine

What this could lead to

If it works, this nerve block could become a simple way to lower the chance of long-term pain after breast cancer surgery.

What could go wrong

This is a small, single-center study with no blinding, so results may not apply widely. The block only targets specific nerves and may not prevent all chronic pain.

Conditions

The condition(s) this trial relates to.

Acute Pain agnosia breast neoplasm Chronic Pain neuralgia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.