Brain waves may guide safer anesthesia for seniors
NCT ID NCT05790720
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to create a new way to give propofol, a common anesthesia drug, to adults over 65. Researchers will monitor brain activity (EEG) and consciousness levels in 36 older adults during surgery to build a model that predicts the right dose. The goal is to improve safety and reduce side effects in this age group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Propofol
- What this could lead to
- If successful, this could lead to safer and more precise anesthesia dosing for older adults, reducing risks during surgery.
- What could go wrong
- This is a small, early-phase study (36 participants) focused on building a model, not testing a treatment. The results may not apply to all older adults or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients undergoing non-cardiac elective surgery requiring general anesthesia * American Society of Anesthesiologists Physical Status I to III Exclusion Criteria: * Patients undergoing emergency surgery * Neurosurgical patients * History of alcohol abuse or recreational drug use * Known allergie to Propofol * Body mass index ≥ 35 Kg m-2 * Unstable heart failure
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Pontificia Universidad Católica de Chile
RECRUITINGSantiago, Santiago Metropolitan, 8330024, Chile
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