Aged

This phase 3 trial tests whether injecting NBTXR3 nanoparticles into tumors before radiation therapy can improve outcomes for elderly patients with advanced head and neck cancer who cannot receive chemotherapy. About 500 participants will be randomly assigned to receive either ra…

This study is testing a new treatment model for elderly patients (65+) with early-stage lung cancer. It combines advanced surgical techniques, personalized care before and after surgery, and rehabilitation programs. The goal is to improve survival and reduce complications. Resear…

This study tests whether a special type of artificial light that changes throughout the day can improve sleep, body clock function, and overall well-being in frail older adults. Researchers will enroll 300 people over age 65 who are staying in hospital rooms equipped with this dy…

This study looks at whether providing acute medical care at home for people aged 75 and older is as effective as sending them to the emergency department. Researchers will compare health outcomes, including hospital stays and death rates, between those who received home-based car…

This study will give 1,080 older adults with disabilities a smart wristband to wear for 8 weeks. The device tracks steps, heart rate, and fatigue, and shares data with caregivers and healthcare providers. Researchers want to see if this improves physical activity, daily functioni…

This study looks at two sedative drugs, remimazolam and midazolam, used to put older adults (65+) to sleep for non-cardiac surgery. The goal is to see which one offers better heart and blood pressure stability, faster recovery, and fewer complications like confusion after surgery…

This study looks at 2,000 adults aged 50+ to see if certain blood cell mutations are tied to aging and heart disease, beyond just getting older. Researchers will compare blood and mouth cells to find mutations and track health over time. The goal is to understand these mutations'…

This study aims to create a new way to give propofol, a common anesthesia drug, to adults over 65. Researchers will monitor brain activity (EEG) and consciousness levels in 36 older adults during surgery to build a model that predicts the right dose. The goal is to improve safety…

This study is testing whether measuring skin conductance—a sign of nervous system activity—can predict dangerous drops in blood pressure after spinal anesthesia in elderly cancer patients. Researchers will monitor 102 patients aged 65 and older undergoing urologic cancer surgery.…