Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Simple leg sleeves may cut need for blood pressure drugs during surgery

NCT ID NCT06950606

Disease control Sponsor: Universitätsklinikum Hamburg-Eppendorf Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 27, 2026 · Updated 3 times

Summary

This completed trial tested whether inflatable leg sleeves (pneumatic compression) could reduce the amount of norepinephrine, a drug that raises blood pressure, needed during non-cardiac surgery. 238 adults aged 45 and older were randomly assigned to receive either the leg sleeves or standard care. The goal was to see if the sleeves help keep blood pressure stable with less medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pneumatic leg compression device
What this could lead to
If it works, this could offer a simple, non-drug way to reduce the need for blood pressure medication during surgery.
What could go wrong
This is a small, single-center pilot study, so results may not apply broadly. The device may not significantly reduce medication needs or could cause discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

238 people

The number who actually took part.

Started

May 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Consenting patients ≥45 years scheduled for elective non-cardiac surgery under general anesthesia that is expected to last ≥60 minutes Exclusion Criteria: Patients with the following exclusion criteria: * high risk surgery according to the 2022 ESC guideline "Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery" * Surgery in which pneumatic calve compression is indicated according to ERAS guidelines * Surgery which interferes with the installation or correct function of PLC * Sepsis (according to current Sepsis-3 definition) * Pregnancy * Congestive heart failure NYHA III/IV * American Society of Anesthesiologists (ASA) physical status classification V or VI * Interference of PLC and patient positioning (e.g.; extreme Trendelenburg positioning, lithotomy positioning) * Contraindications for the use of PLC according to the German guideline13 (e.g., extensive thrombophlebitis, thrombosis or suspected thrombosis of the lower limbs, erysipelas, acute phlegmon, limb compartment syndrome, severe uncontrolled arterial hypertension, lymphatic drainage disorder proximal to PLC, extensive open soft tissue trauma, autoimmune blistering skin conditions such as IgA bullous dermatosis or bullous pemphigoid)

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hypotension during surgery are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypotension during surgery

Contacts and locations

Locations

  • University Medical Center Hamburg-Eppendorf

    Hamburg, Free and Hanseatic City of Hamburg, 20246, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.