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Nose surgery blood pressure study aims to protect kidneys

NCT ID NCT07662577

Knowledge-focused Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at 110 adults having nose surgery (septoplasty) to see if different blood pressure targets during surgery affect kidney injury. Patients were split into two groups: one with a lower blood pressure target (50-57 mmHg) and one with a higher target (58-65 mmHg). Kidney injury was measured using a blood test called NGAL. The goal was to find out which blood pressure range is safer for the kidneys.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors choose safer blood pressure levels during nose surgery to protect the kidneys.
What could go wrong
This is a small, completed study with no direct treatment benefit. Results may not apply to other surgeries or patients with health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

110 people

The number who actually took part.

Started

May 2019

Finished

Aug 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years * Scheduled for elective septoplasty under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-II * Planned controlled hypotension during surgery * Provided written informed consent Exclusion Criteria: * Body mass index (BMI) \> 35 kg/m² * History of hypertension * Diabetes mellitus * Coronary artery disease * Cerebrovascular disease * Carotid artery stenosis * Vertebrobasilar insufficiency * Pre-existing renal dysfunction * Anemia * Hypovolemia * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

acute kidney injury hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypotension during surgery Kidney injury NGAL

Contacts and locations

Locations

  • FSMTRH

    Istanbul, Ataşehir, 34752, Turkey (Türkiye)

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