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Gentle pilates tested as a pain relief tool for bendy joints

NCT ID NCT07464093

Symptom relief Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 20, 2026 · Updated 2 times

Summary

This study tests whether Pilates, a gentle mind-body exercise, can help manage pain and other symptoms in people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder. One hundred adults with persistent pain will be randomly assigned to either Pilates classes or educational seminars. The main goal is to see if the program is feasible and acceptable, with pain levels also measured as a secondary outcome.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pilates exercise
What this could lead to
If it works, this could point toward a gentle exercise option to help manage pain and improve daily life for people with hypermobility conditions.
What could go wrong
This is a small, early feasibility study, not a large trial. It may not show clear benefits, and results may not apply to everyone with hypermobility.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ≥ 18 years old; * Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD; * Self-reported persistent pain ≥ 3 months; * A minimum of 3/10 self-reported pain intensity in the past week * Able to get on and off the floor without assistance; * Able to communicate fluently in English; and * Able to provide written, informed consent Exclusion Criteria: * Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months; * Recent surgery or acute bone, joint or nerve injury (\<6 months); * Have a history of a severe or progressive neurological or movement disorder; * Pregnant, planning to become pregnant during the study, or currently breast feeding; * Unable to get on and off the floor without assistance; * Unable to complete study procedures due to cognitive impairment; * Unable to provide written, informed consent; or * Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.

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Conditions

The condition(s) this trial relates to.

Ehlers-Danlos syndrome Ehlers-Danlos syndrome, hypermobility type hypermobility spectrum disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ehlers-Danlos syndrome (EDS) Hypermobile eds (HEDS) Hypermobile spectrum disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Chestnut Hill, Massachusetts, 01467, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.