New drug combo aims to outsmart Hard-to-Treat HER2 cancers
NCT ID NCT07137416
First seen Jan 06, 2026 · Last updated May 01, 2026 · Updated 21 times
Summary
This early-phase trial tests whether adding pidnarulex to the targeted therapy trastuzumab deruxtecan is safe and effective for people with advanced HER2-positive breast cancer or other solid tumors that have spread or can't be removed. About 36 adults whose cancer has stopped responding to standard treatments will receive the combination. The goal is to find the best dose and check for tumor shrinkage.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana-Farber - Harvard Cancer Center LAO
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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