LOCALLY ADVANCED BREAST CARCINOMA
Clinical trials for LOCALLY ADVANCED BREAST CARCINOMA explained in plain language.
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Can switching PARP inhibitors outsmart cancer? new trial aims to find out
Disease control Recruiting nowThis study is testing a drug called talazoparib in people with advanced solid tumors that have specific DNA repair gene mutations. The goal is to see if this PARP inhibitor can shrink tumors or slow their growth, even in patients who have already tried a similar drug. About 36 ad…
Matched conditions: LOCALLY ADVANCED BREAST CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 03:34 UTC
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New drug cocktail targets Hard-to-Treat HER2 cancers
Disease control Recruiting nowThis early-stage trial tests the safety and best dose of combining two drugs—pidnarulex and trastuzumab deruxtecan—in people with advanced breast cancer or other solid tumors that have a protein called HER2. The study includes up to 36 adults whose cancer has spread, cannot be re…
Matched conditions: LOCALLY ADVANCED BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 03:24 UTC
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New ultrasound may predict chemo success early in breast cancer
Diagnosis Recruiting nowThis study tests whether a special contrast-enhanced ultrasound can measure pressure inside breast tumors to predict how well chemotherapy is working. About 200 women with locally advanced breast cancer will get three ultrasounds before and during treatment. The goal is to see if…
Matched conditions: LOCALLY ADVANCED BREAST CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Kibo Nam • Aim: Diagnosis
Last updated May 20, 2026 11:53 UTC
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New bypass procedure may prevent arm swelling in breast cancer patients
Prevention Recruiting nowThis study tests whether a preventive lymphovenous bypass—a rerouting of lymphatic fluid—can stop lymphedema (arm swelling) from developing after lymph node removal. About 252 adults with advanced breast cancer or melanoma will receive the bypass before their scheduled lymph node…
Matched conditions: LOCALLY ADVANCED BREAST CARCINOMA
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated May 26, 2026 03:34 UTC
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New ultrasound marker could make breast cancer surgery more precise
Knowledge-focused Recruiting nowThis early-stage study tests a new type of marker that shows up better on ultrasound for people with breast cancer that has spread to lymph nodes. The marker is placed in the lymph node to help doctors find and remove the right node during surgery. The goal is to see if this mark…
Matched conditions: LOCALLY ADVANCED BREAST CARCINOMA
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 03:26 UTC