Can moving more in the ICU help seniors recover better?
NCT ID NCT03115840
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 312 older adults who survived a critical illness to see how much they moved during their ICU stay. Researchers want to learn if more activity leads to less disability, better mobility, and clearer thinking 3 to 12 months later. The goal is to find ways to improve recovery after a serious illness.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify how activity levels in the ICU influence long-term recovery, pointing toward better rehabilitation strategies for older adults.
- What could go wrong
- This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may be influenced by many factors not controlled for.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 312 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2017
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with medical or surgical critical illness
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. adult patients (≥18 years old), 2. in a medical or surgical ICU at Vanderbilt University Medical Center or The Ohio State University Medical Center, and 3. are being treated for respiratory failure or shock. Exclusion Criteria: 1. Rapidly resolving organ failure criteria, indicated by planned immediate discontinuation of mechanical ventilation, NIPPV, and/or vasopressors at the time of screening for study enrollment, such that the patient will no longer meet inclusion criteria. 2. Cumulative hospital days (ICU plus non-ICU) of five or greater in the last 30 days prior to meeting all inclusion criteria. 3. Inability to live independently at baseline due to acquired or congenital disabling, physical, cognitive or mental health disorder requiring institutionalization (e.g., nursing home, skilled nursing facility, group home, long-term acute care hospital, rehab facility) or any patient who resides outside an institution with an inability to walk without the assistance of another person (e.g., patients with quadriplegia, paraplegia, double amputees, those with residual paralysis from stroke). 4. Acute or subacute severe neurologic (e.g., stroke anoxic injury, spinal cord injury) that is expected to prevent the patient from living independently after hospital discharge. 5. Body mass index \>50 6. Active substance abuse or psychotic disorder (e.g., schizophrenia or schizo-affective disorder), recent (within the past 6 months) serious suicidal gesture necessitating hospitalization 7. Blindness, deafness, or inability to understand English that will preclude follow-up evaluation. Patients with laryngectomies and those with hearing impairments are eligible for enrollment if their medical condition permits them to communicate with research staff. 8. Expected death within 24 hours of enrollment or lack of commitment to aggressive treatment by family or the medical team (e.g., likely to withdraw life support measures within 24 hours of screening). 9. Prisoners 10. Patients who live further than 200 miles from an enrolling center and who do not regularly visit the area. 11. Patients who are homeless and have no secondary contact person available 12. Current enrollment in a study that does not allow co-enrollment 13. Inability to obtain informed consent from the patient or an authorized representative within 72 hours of meeting all inclusion criteria for the following reasons: 1. Attending physician refusal 2. Patient and/or surrogate refusal 3. 72-hour period of eligibility was exceeded before the patient was screened 4. Patient unable to consent and no surrogate available within 72 hours of meeting all inclusion criteria 14. Confirmed or suspected COVID-19 per local guidelines at the time of screen.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Ohio State University Medical Center
Columbus, Ohio, 43210, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37212, United States
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