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C-Section blood pressure: which dose of phenylephrine works best?

NCT ID NCT07420127

Disease control Sponsor: Rawalpindi Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing two different doses of phenylephrine (75 vs 50 micrograms) given alongside oxytocin during C-sections to prevent low blood pressure. Oxytocin helps the uterus contract after delivery but can cause blood pressure to drop. The trial will enroll 112 women having planned C-sections under spinal anesthesia and compare how many have hypotensive episodes and how much extra phenylephrine is needed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Phenylephrine
What this could lead to
If it works, this could identify the best dose of phenylephrine to prevent dangerous drops in blood pressure during C-sections.
What could go wrong
This is a small, early-phase trial comparing two doses, so it may not find a clear winner. Results may not apply to all women having C-sections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 112 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Females having a singleton pregnancy Patients planned for elective cesarean section under spinal anesthesia Exclusion Criteria: * Patients having a placental abnormality * Patients taking beta-blocker and vasodilator therapy * Patients with hypertensive disorder

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cesarean birth Phenylephrine

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Anesthesia, Holy Family Hospital, Rawalpindi

    RECRUITING

    Rawalpindi, Punjab Province, 46000, Pakistan

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