C-Section blood pressure: which dose of phenylephrine works best?

NCT ID NCT07420127

Recruiting now Disease control Sponsor: Rawalpindi Medical College Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing two different doses of phenylephrine (75 vs 50 micrograms) given alongside oxytocin during C-sections to prevent low blood pressure. Oxytocin helps the uterus contract after delivery but can cause blood pressure to drop. The trial will enroll 112 women having planned C-sections under spinal anesthesia and compare how many have hypotensive episodes and how much extra phenylephrine is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Phenylephrine
What this could lead to: If it works, this could identify the best dose of phenylephrine to prevent dangerous drops in blood pressure during C-sections.
What could go wrong: This is a small, early-phase trial comparing two doses, so it may not find a clear winner. Results may not apply to all women having C-sections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CESAREAN BIRTH PHENYLEPHRINE

Contacts and locations

Locations

Department of Anesthesia, Holy Family Hospital, Rawalpindi
RECRUITING

Rawalpindi, Punjab Province, 46000, Pakistan

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