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Wrist surgery showdown: to remove or not remove a small bone?

NCT ID NCT04580225

Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of wrist fusion surgery for people with post-traumatic wrist arthritis. One surgery fuses four wrist bones and removes the scaphoid. The other fuses three or two bones and also removes the triquetrum. The goal is to see which approach gives better grip strength and wrist movement over a year. 170 participants will be randomly assigned to one of the two surgeries.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Partial wrist fusion surgery (with or without triquetral bone removal)
What this could lead to
If this trial succeeds, it could help surgeons choose the best wrist fusion technique to improve grip strength and movement for people with wrist arthritis.
What could go wrong
This is a surgical technique comparison, not a new drug or cure. Results may not apply to all types of wrist arthritis, and individual outcomes vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 170 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2021

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant has a stage II or III scapholunate advanced collapse (SLAC) or scaphoid nonunion advanced collapse (SNAC) wrist and is a surgical candidate for the included surgical interventions Exclusion Criteria: * Participant has been diagnosed with other forms of wrist arthritis other than SLAC or SNAC * Participant has significant arthritis of the ipsilateral hand/finger joint(s), major joint trauma, previous major wrist surgery, infection or neuromuscular pathology affecting the function of the ipsilateral upper extremity or ability to make a fist * Participant has a physical or mental health condition preventing completion of consent or questionnaires * Participant does not speak/read/understand English * Participant has no fixed address or means of contact * Participant is unwilling to complete necessary follow-ups * Surgeon concludes that eligible salvage techniques are not appropriate at the time of surgery (based on injury characteristics or concomitant wrist pathology)

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Conditions

The condition(s) this trial relates to.

arthritic joint disease arthropathy musculoskeletal system disorder osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthritis Joint diseases Musculoskeletal diseases Post-traumatic; arthrosis Scaphoid nonunion Scapholunate advanced collapse Wrist arthritis Wrist arthropathy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Lawson Health Research Institute

    RECRUITING

    London, Ontario, Canada

  • South Health Campus

    RECRUITING

    Calgary, Alberta, Canada

  • The Ottawa Hospital - Civic Campus

    RECRUITING

    Ottawa, Ontario, Canada

  • University of Saskatchewan

    RECRUITING

    Saskatoon, Saskatchewan, Canada

  • Western Hand & Upper Limb Facility, Sturgeon Community Hospital

    RECRUITING

    St. Albert, Alberta, Canada

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