MUSCULOSKELETAL DISEASES

This program provides access to an investigational drug, AOC 1044, for people with Duchenne muscular dystrophy (DMD) whose genetic mutation can be treated by skipping exon 44. It is for eligible patients aged 6 and older living in the US. The goal is to offer treatment while gath…

This study aims to develop faster and more reliable MRI scans to detect early signs of osteoarthritis and other joint diseases before they show up on X-rays. Researchers will test these new methods on 88 healthy volunteers and patients with ACL tears or early cartilage problems a…

This study compares two treatments for carpal tunnel syndrome: an ultrasound-guided injection around the median nerve and a small-incision surgery to release the nerve. Researchers will enroll 60 people with mild to severe carpal tunnel and measure their pain and symptoms at 4 an…

This study compares two types of wrist fusion surgery for people with wrist arthritis caused by past injuries. 170 adults with stage II or III SLAC or SNAC wrist will be randomly assigned to have either a four-corner fusion or a three-corner fusion (which also removes a small bon…

This study tests whether tiny, dissolvable beads called SakuraBead can safely reduce heel pain in people with plantar fasciitis. About 45 adults with thickened, painful tissue in the foot will get either the bead procedure or standard care. The goal is to see if the beads help mo…

This study is translating the Generic Functional Index, a questionnaire that measures how well people can perform daily activities, into Turkish. Researchers will test the translated version on 200 adults with musculoskeletal disorders (like arthritis or back pain) to make sure i…

This study aims to create a secure national database by collecting routine health information from 22,000 adults with muscle or joint problems seen in community or primary care. Researchers will use this data to develop dashboards and reports that help clinics track and improve t…

This study gathers firsthand information from 1000 adults with rheumatic or musculoskeletal diseases across Europe. Participants fill out online surveys about their healthcare, social life, and work. The goal is to help researchers and doctors better understand the burden of thes…

This study looks at how common muscle and joint pain is among dentists and dental students, and how much they know about ergonomics (working in a way that prevents injury). About 90 people will fill out a questionnaire about pain in different body areas over the past year. The go…

This study follows 10,000 adults aged 18 and older over many years to see if a set of health measurements can predict how long people live and what diseases they may get. Participants undergo health screenings and are followed until death. The goal is to better understand aging a…

This study looks at how carpal tunnel syndrome (CTS) affects sleep quality. Researchers will compare 120 people with CTS to healthy volunteers using ultrasound and sleep questionnaires. The goal is to understand the link between nerve compression and poor sleep, without offering …

This study looks at how changing the heel height and stiffness of an ankle-foot brace (AFO) affects walking in people who use one daily. About 40 adults with leg injuries or nerve problems will walk with different heel cushions while researchers measure motion, comfort, and pain.…