MUSCULOSKELETAL DISEASES

This study looked at the long-term safety of a drug called AOC 1001 in adults with myotonic dystrophy type 1 (DM1), a genetic muscle disease. 37 people who completed an earlier study received multiple doses of the drug by IV. Researchers tracked side effects and measured drug lev…

This study tested a new medicine called LEVI-04 to see if it can reduce pain in people with knee osteoarthritis. About 518 adults with knee pain took either the drug or a placebo. The main goal was to measure pain changes using standard pain scales. The trial is complete, and res…

This study looked at whether high-intensity laser therapy can reduce shoulder pain and improve movement in people who had a stroke and have weakness on one side (hemiplegia). Forty participants aged 50-85 with lasting shoulder pain were treated. The goal was to see if the laser c…

This study looked at 116 adults with chronic muscle or joint pain to understand how their beliefs about pain, their spiritual well-being, and their views on complementary treatments (like acupuncture or herbal medicine) are related. Participants completed questionnaires about the…

This study looked at how a 6-month strength training program affects bone health, sleep patterns, and quality of life in healthy adults aged 30 and older. Researchers measured changes in muscle mass, body composition, and markers of bone turnover. The goal was to understand if re…

This study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint problems in the emergency room, compared to standard care from doctors. Over 100 patients with conditions like back pain or sprains were randomly assigned to eit…

This study followed 225 people who had ACL knee surgery to see what factors lead to arthritis years later. Researchers checked knee structure, pain, and quality of life at 2 and 10 years after surgery. The goal is to understand why some patients develop arthritis and others do no…

This study tested a special navigation system that helps surgeons balance soft tissues during knee replacement surgery. Forty adults received a Medacta GMK Sphere knee implant with this system. The goal was to see if the system improves knee function and safety, measured by the O…

This study looked at how a very low-carb ketogenic diet compares to a Mediterranean diet for bone health and muscle function in older adults. Twelve postmenopausal men and women participated in this short-term pilot trial. The goal was to gather initial data on safety and benefit…

This study looked at 110 medical secretaries to see how their desk setup, posture, and work habits relate to muscle and joint pain. Participants filled out surveys about their work environment and any aches they had. The goal was to find links between poor ergonomics and pain in …

This study aimed to create a better way to help older adults with muscle, bone, or nerve problems who are at risk of falling. Researchers worked with 11 seniors to understand their health profiles, test their balance and walking, and try a special exercise program called OTAGO. T…

This study looked at how often nursing home residents over 65 have joint complaints like pain or swelling. Researchers examined 100 residents, some with dementia and some without, to count tender or swollen joints. The goal was to better understand these issues in a group that is…